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# GATE Biotechnology Syllabus

Indian Institute of Technology, Madras (IITM) has prescribed GATE Biotechnology Syllabus. Those who will appear in GATE Exam 2019 may download updated GATE BT Syllabus PDF. Along with this, we are also providing GATE Biotechnology Exam Pattern.

Computer based exam will be organized by IIT Madras on 02nd, 03rd, 09th & 10th February 2019. There will be multiple choice type questions and numerical answer type questions in GATE Exam. General aptitude and the engineering mathematics section are compulsory in GATE.

GATE Biotech Syllabus:

GATE Exam is considered to be toughest test in all India. Aspirants may get GATE Biotechnology Syllabus 2019 & know in detail about topics and sub-topics from which the questions will be asked in Graduate Aptitude Test in Engineering.

To gain more details about GATE Biotechnology 2019 Syllabus & GATE BT Syllabus PDF, take a look of below page created by team of www.recruitmentinboxx.com Get detailed GATE Biotechnology Exam Syllabus from this page.

GATE Important Dates 2019

 Events GATE 2019 Date GATE Registration Will Begin From 01-09-2018 Last Date For GATE 2019 Registration 21-09-2018 Extended Closing Date 01-10-2018 GATE 2019 Exam Date 02nd, 03rd, 09th & 10th February 2019

## GATE Biotechnology Syllabus

GATE Biotechnology Syllabus 2019:

There are five sections in GATE Biotechnology BT Syllabus that are listed below:

• Engineering Mathematics Linear Algebra
• General Biotechnology
• Recombinant DNA Technology
• Plant and Animal Biotechnology
• Bioprocess Engineering and Process Biotechnology

Section 1: Engineering Mathematics Linear Algebra

Matrices and determinants, Systems of linear equations, Eigen values and Eigen vectors, Calculus: Limit, continuity and differentiability, Partial derivatives, Maxima and minima, Sequences and series, Test for convergence, Fourier series. Differential Equations: Linear and nonlinear first order ODEs, higher order ODEs with constant coefficients, Cauchy’s and Euler’s equations, Laplace transforms, PDE-Laplace, heat and wave equations. Probability and Statistics: Mean, median, mode and standard deviation, Random variables, Poisson, normal and binomial distributions, Correlation and regression analysis. Numerical Methods: Solution of linear and nonlinear algebraic equations, Integration of trapezoidal and Simpson’s rule, Single and multistep methods for differential equations.

GATE Biotechnology Syllabus Section 2: General Biotechnology

Biochemistry: Biomolecules-structure and functions; Biological membranes, structure, action potential and transport processes; Enzymes- classification, kinetics and mechanism of action; Basic concepts and designs of metabolism (carbohydrates, lipids, amino acids and nucleic acids) photosynthesis, respiration and electron transport chain; Bioenergetics

Microbiology: Viruses- structure and classification; Microbial classification and diversity (bacterial, algal and fungal); Methods in microbiology; Microbial growth and nutrition; Aerobic and anaerobic respiration; Nitrogen fixation; Microbial diseases and host-pathogen interaction

Cell Biology: Prokaryotic and eukaryotic cell structure; Cell cycle and cell growth control; Cell-Cell communication, Cell signaling and signal transduction

Molecular Biology and Genetics: Molecular structure of genes and chromosomes; Mutations and mutagenesis; Nucleic acid replication, transcription, translation and their regulatory mechanisms in prokaryotes and eukaryotes; Mendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extra chromosomal inheritance; Microbial genetics (plasmids, transformation, transduction, conjugation); Horizontal gene transfer and Transposable elements; RNA interference; DNA damage and repair; Chromosomal variation; Molecular basis of genetic diseases

Analytical Techniques: Principles of microscopy-light, electron, fluorescent and confocal; Centrifugation- high speed and ultra; Principles of spectroscopy-UV, visible, CD, IR, FTIR, Raman, MS,NMR; Principles of chromatography- ion exchange, gel filtration, hydrophobic interaction, affinity, GC,HPLC, FPLC; Electrophoresis; Microarray

Immunology: History of Immunology; Innate, humoral and cell mediated immunity; Antigen; Antibody structure and function; Molecular basis of antibody diversity; Synthesis of antibody and secretion; Antigen-antibody reaction; Complement; Primary and secondary lymphoid organ; B and T cells and macrophages; Major histocompatibility complex (MHC); Antigen processing and presentation; Polyclonal and monoclonal antibody; Regulation of immune response; Immune tolerance; Hypersensitivity; Autoimmunity; Graft versus host reaction.

Bioinformatics: Major bioinformatic resources and search tools; Sequence and structure databases; Sequence analysis (biomolecular sequence file formats, scoring matrices, sequence alignment, phylogeny); Data mining and analytical tools for genomic and 11 of 72 proteomic studies; Molecular dynamics and simulations (basic concepts including force fields, protein-protein, protein-nucleic acid, protein-ligand interaction)

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Section 3: Recombinant DNA Technology

Restriction and modification enzymes; Vectors; plasmid, bacteriophage and other viral vectors, cosmids, Ti plasmid, yeast artificial chromosome; mammalian and plant expression vectors; cDNA and genomic DNA library; Gene isolation, cloning and expression ; Transposons and gene targeting; DNA labeling; DNA sequencing; Polymerase chain reactions; DNA fingerprinting; Southern and northern blotting; In-situ hybridization; RAPD, RFLP; Site-directed mutagenesis; Gene transfer technologies; Gene therapy

GATE Biotech Syllabus Section 4: Plant and Animal Biotechnology

Totipotency; Regeneration of plants; Plant growth regulators and elicitors; Tissue culture and Cell suspension culture system: methodology, kinetics of growth and, nutrient optimization; Production of secondary metabolites by plant suspension cultures; Hairy root culture; transgenic plants; Plant products of industrial importance Animal cell culture; media composition and growth conditions;

Animal cell and tissue preservation; Anchorage and non-anchorage dependent cell culture; Kinetics of cell growth; Micro & macro-carrier culture; Hybridoma technology; Stem cell technology; Animal cloning; Transgenic animals

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Section 5: Bioprocess Engineering and Process Biotechnology

Chemical engineering principles applied to biological system, Principle of reactor design, ideal and non-ideal multiphase bioreactors, mass and heat transfer; Rheology of fermentation fluids, Aeration and agitation; Media formulation and optimization; Kinetics of microbial growth, substrate utilization and product formation; Sterilization of air and media; Batch, fed-batch and continuous processes; Various types of microbial and enzyme reactors; Instrumentation control and optimization; Unit operations in solid-liquid separation and liquid-liquid extraction; Process scale-up, economics and feasibility analysis

Engineering principle of bioprocessing- Upstream production and downstream; Bioprocess design and development from lab to industrial scale; Microbial, animal and plant cell culture platforms; Production of biomass and primary/secondary metabolites; Biofuels, Bioplastics, industrial enzymes, antibiotics; Large scale production and purification of recombinant proteins; Industrial application of chromatographic and membrane based bioseparation methods; Immobilization of biocatalysts (enzymes and cells) for bioconversion processes; Bioremediation-Aerobic and anaerobic processes for stabilization of solid / liquid wastes.

Also CheckGATE Previous Year Question Paper

Syllabus for General Aptitude (GA)

COMMON TO ALL PAPERS:

Verbal Ability: English grammar, sentence completion, verbal analogies, word groups, instructions, critical reasoning and verbal deduction.

Numerical Ability: Numerical computation, numerical estimation, numerical reasoning and data interpretation.

GATE Biotechnology 2019 Exam Pattern:

Graduate Aptitude Test in engineering examination consists of a single paper of 3-hour duration in which it includes 65 questions which carry maximum of 100 marks. The question paper will consist of both multiple choice questions (MCQ) and numerical answer type (NAT) questions. So, start your practice through updated GATE Biotechnology Syllabus.

 GATE 2019 paper Pattern for Biotechnology Engineering Mathematics Engineering Mathematics will have 13% of total marks weigh General Aptitude General Aptitude will have 15% of total marks weigh Subject questions Subject questions will have rest 72% of total marks weigh

Get More Details on: GATE Exam Pattern

Practice Books For GATE Biotechnology Exam 2019:

 Biotechnology Books Practice Papers Verbal/ Numerical Books Microbiology by LM Prescott, JP Harley, DA Klein·         Lehninger Principles of Biochemistry by Nelson and Cox·         Biological Science by NPO Green, GW Stout, DJ TaylorReview of Medical Physiology by William F. Ganong Life Science- Fundamental & practice by Pranav Kumar & Usha Mina Principles and Techniques by Keith Wilson and John Walker Gene Cloning and DNA Analysis by TA Brown Cell & Molecular Biology by G Karp GATE 2015 Solved Paper 2000- 2014 Biotechnology by GK publications·         GATE Biotechnology 2015 by GK Publications· GATE Biotechnology by Arihant PublicationsGATE Tutor- Biotechnology 2015 by Arihant Publications Quantitative Aptitude by Dr. R.S. Aggarwal·         Objective English by hari Mohan Prasad, Uma Rani Sinha·         How to Prepare for Quantitative Aptitude by Arun SharmaA modern Approach by Verbal & Non- verbal reasoning by Dr. R.S. Aggarwal

Get Here Complete: GATE Study Material

Procedure to get GATE Biotechnology Syllabus 2019 PDF:

• Visit official website of Graduate Aptitude Test in engineering that is www.gate.iitm.ac.in
• Hit on ‘Pre Exam’ tab accessible at top menu bar.
• From drop down list, choose ‘Syllabi’ link for GATE Biotech Syllabus.
• At new page, you may press on ‘BT: Biotechnology’ link.
• GATE BT Syllabus PDF will open up facing you.
• Download GATE Biotechnology Exam Syllabus & access hard copy of it for exam preparation.

Press Here For GATE Biotechnology Syllabus PDF

Press Here For GATE Biotechnology Syllabus Official Link

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